Breakthrough Relief for Depression: How Spravato® Is Changing Lives

Spravato for Depression: What You Need to Know

Spravato® (esketamine) is a prescription nasal spray approved by the FDA for adults dealing with treatment-resistant depression (TRD) and major depressive disorder (MDD) with suicidal thoughts or behaviors. Unlike traditional antidepressants, which can take weeks to work, Spravato offers fast-acting relief by targeting a different pathway in the brain.

Spravato is derived from ketamine, an anesthetic that has shown significant promise in rapidly reducing depressive symptoms. It is not the same as intravenous ketamine therapy, though both act on the glutamate system, which plays a role in mood regulation.

Who Can Benefit from Spravato?

Spravato is specifically approved for adults who meet either of the following criteria:

• Have tried two or more antidepressants without relief (treatment-resistant depression)

• Are experiencing suicidal thoughts and require rapid intervention

Patients must be assessed and approved by a licensed behavioral health provider and receive treatment at a certified Spravato treatment center, such as Pinnacle Care.

How Spravato Works

Traditional antidepressants increase neurotransmitters like serotonin and norepinephrine. Spravato, on the other hand, works on the glutamate system—one of the brain’s most prevalent neurotransmitters. By blocking NMDA receptors, Spravato helps reset brain connections and restore mood regulation, often within hours to days instead of weeks.

It is administered nasally in a clinical setting under medical supervision. Patients are monitored for 2 hours following each dose due to potential side effects like dizziness or dissociation.

Symptoms Spravato Can Help Manage

Spravato may offer relief for a range of treatment-resistant symptoms, including:

• Persistent sadness or hopelessness

• Suicidal thoughts

• Lack of motivation or energy

• Emotional numbness

• Sleep disturbances related to depression

• Anxiety symptoms associated with MDD

Many patients begin to feel a significant improvement in mood after the first few doses—a dramatic shift for those who have lived with long-term, unresponsive depression.

What to Expect at Pinnacle Care

At Pinnacle Care, your Spravato treatment will include:

• Comprehensive psychiatric evaluation to determine candidacy

• On-site administration and monitoring by licensed professionals

• A calm, safe, and private setting for treatment

• Coordination with your therapist or medication provider for continuity of care

We are proud to be a certified provider of Spravato in Oklahoma, offering this life-changing treatment for those who need it most.

Is Spravato Right for You?

If you or a loved one have struggled with depression that hasn’t responded to medication—or if you’re in urgent need of symptom relief—Spravato might be the breakthrough you’ve been waiting for.

Get started today; request your appointment in seconds and see if you qualify for this advanced treatment. So many people have benefitted from this breakthrough treatment. Request your appointment today or click here to learn more about Spravato at Pinnacle Care.